Sonicators
Sonicators
Devices employing ultrasonic waves to homogenize samples, particularly cells/subcellular structures in suspension; also includes accessories and support devices such as power options, probes, sound enclosures, and more.
Sonication uses sound waves to disrupt substances. An electrical signal is converted into a vibration that can mix solutions, dissolve solids into liquids, and remove dissolved gas from liquids. When sound waves at ultrasonic frequencies (>20 kHz) are used, the process is called ultrasonification.
In the laboratory, sonication can be applied via an ultrasonic probe, also called a sonicator or sonic dismembrator. The probe creates sound waves that produce pressure, causing liquid streaming and rapid bubble formation. The bubbles are very small at the start, but grow and coalesce, vibrate violently, and then collapse in the process called cavitation.
The shear from the cavitation and the liquid eddying caused by the vibrating transducer (probe) can hasten chemical reactions and break intermolecular bonds. This speeds dissolution and can be used for samples that cannot easily be stirred. Sonication is also used to disrupt or deactivate biological materials. Cells release their contents when cell walls are disturbed (sonoporation) and DNA molecules can be reduced to smaller fragments.
Effective disruption depends on a number of variables, including tip amplitude and intensity; temperature; cell concentration; pressure; and vessel capacity and shape
Sonication is used in the pharmaceutical, food and pesticide, and cosmetic industries as well as for inks, paints, and coatings, wood and wood treatment, and metalworking. Other uses include: breaking up soil aggregates; nanoparticle, nanoemulsion, or nanocrystal production; wastewater purification; de-gassing; extracting seaweed polysaccharides, plant oils, anthocyanins, and antioxidant; biofuel production; de-sulfuring crude oils; and extracting microfossils from rock.
Fisherbrand™ 505 Sonicator with Probe
Use this high powered sonicator for various applications and sample volumes. Fisherbrand™ Sonicators with Probe are ideal for cell disruption, nanoparticle dispersion, homogenisation and sample preparation.
Sonics Materials VC-505 Ultrasonic Processor
The VC-505 Ultrasonic Processor is extremely capable and versatile, it can safely process a wide range of organic and inorganic materials – from microliters to liters.
Fisherbrand™ Model 120 Sonic Dismembrator
Programable system ideal for small volume liquid processing. There are 3 probe size options available which allow for processing 0.2-50 mL volumes.
Fisherbrand™ Q705 Sonicator with Probe
Use this high powered sonicator for any application and sample volume. Fisherbrand™ Sonicators are ideal for cell disruption, nanoparticle dispersion, DNA shearing/ChIP and homogenization.
Fisherbrand™ Q705 Sonicator without Probe
Guarantees more efficient operation, sample-to-sample consistency and most importantly, a reliable end result. Fisherbrand™ Q705 Sonicator without Probe is the most technologically advanced sonicator available today.
Fisherbrand™ Model 50 Sonic Dismembrator
Economical, small volume cell disruptor.
Fisherbrand™ Q55 Sonicator without Probe
Effective for standard cell disruption and many other small-volume applications. Fisherbrand™ Q55 Sonicator is a compact and cost-effective ultrasonic processor that will occupy less bench space than any unit on the market.
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Fisherbrand™ Q500 Sonicator without Probe
Providing programmable operation and a digital display of operating parameters. Fisherbrand™ Q500 Sonicator without Probe is excellent for nanoparticle dispersion, creating emulsions, cell lysis and homogenization applications.
Sonics Materials VCX 750 Ultrasonic Microprocessor
The 750 Watt Ultrasonic Processor is for small and medium volume applications and is ideal for safely processing a wide range of organic and inorganic materials from 250 microliters to 1 liter.
Branson Ultrasonics™ Sonifier™ SFX150 Cell Disruptor
Branson Ultrasonics Sonifier™ SFX150 Cell Disruptor with advanced controls gives more precise control over all critical elements of experiment.
Heidolph Instruments Boss Head
Suitable for stand rods with up to 13.1 mm maximum diameter
Sonics Materials VCX 500 Ultrasonic Microprocessor
Safely processes a wide range of organic and inorganic materials, from 250 microliters to 1 liter.
Branson Ultrasonics™ Sonifier™ SFX250/SFX550 Cell Disruptors
Advanced controls gives more precise control over all critical elements of experiment.
Fisherbrand™ Probes for Model 50 and 120 Sonic Dismembrator
Image shows (left to right): 4423, 4422, 4435.
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