Test
Inhibits NF-κB activation
CaM kinase II inhibitor; water soluble version of KN 93 (Cat. No. 1278).
Potassium channel modulator; exerts subtype-specific effects
Potent ROCK inhibitor
Potent and selective polynucleotide kinase/phosphatase (PNKP) inhibitor
Potent and selective negative allosteric modulator at mGlu1; also mGlu1 inverse agonist
Potent VEGFR inhibitor; also inhibits other RTKs
S1P2 receptor antagonist
Glucokinase activator
Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest
Potent and selective Lck and Src inhibitor; also inhibits SIK
Highly selective and potent non-peptide NPY Y5 receptor antagonist
Potent and selective K2P3.1 (TASK-1) channel blocker
Highly potent and selective JNK3 inhibitor
Selective inhibitor of Rac1-GEF interaction; antioncogenic