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  6. Thermo Scientific Chemicals 2',3'-Dideoxycytidine, 98+%

Thermo Scientific Chemicals 2',3'-Dideoxycytidine, 98+%

Product Code. 11332906
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Quantity:
50 mg
250 mg

Description

2',3'-Dideoxycytidine in cells, it is phosphorylated to the active triphosphate form, ddCTP, which acts as a substrate for HIV reverse transcriptase (Ki = 51 nM). It incorporates into viral DNA where it terminates chain elongation when the missing hydroxyl group is encountered. It is also is used as a DNA chain-terminating nucleotide for DNA sequencing methods based on the Sanger chain-termination method.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 7481-89-2
Molecular Formula C9H13N3O3
Molecular Weight (g/mol) 211.22
MDL Number MFCD00012188
InChI Key WREGKURFCTUGRC-KGQMAECUNA-N
Synonym zalcitabine, 2',3'-dideoxycytidine, dideoxycytidine, ddcyd, hivid, ddc, cytidine, 2',3'-dideoxy, zalcitibine, ddc antiviral, 4-amino-1-2r,5s-5-hydroxymethyl tetrahydrofuran-2-yl pyrimidin-2 1h-one
PubChem CID 24066
ChEBI CHEBI:10101
SMILES NC1=NC(=O)N(C=C1)[C@H]1CC[C@@H](CO)O1

Specifications

Melting Point 216°C to 220°C
Packaging Glass bottle
Quantity 250 mg
Beilstein 654956
Solubility Information Soluble in water (76.4mg/ml at 25°C),DMSO (42mg/ml at 25°C),and ethanol (<1mg/ml at 25°C).
IUPAC Name 4-amino-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Formula Weight 211.22
Percent Purity ≥98%
Physical Form Solid
Chemical Name or Material 2′,3′-Dideoxycytidine

RUO – Research Use Only

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