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  8. 2-Iodoacetamide, 98%, stab. with ca 5-8% water, Thermo Scientific Chemicals

2-Iodoacetamide, 98%, stab. with ca 5-8% water, Thermo Scientific Chemicals

Product Code. 11467736
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Quantity:
5 g
25 g
100 g
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Description

Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Alkylating agent used in peptide mapping because it covalently binds with the thiols in cysteine to prevent disulfide bond formation2-Iodoacetamide is used as an electrophile for covalent modification of nucleophilic residues on proteins such as cysteine, methionine and histidine. It is used to bind with thiol group of cysteine, thereby it protects the formation disulfide bonds. It is involved as an inhibitor of deubiquitinase enzymes (DUBs). Further, it acts as an alkylating sulfhydryl reagent.

Solubility
Soluble in water, dimethyl formamide and ethanol. Slightly soluble in methanol.

Notes
Store in a cool place. Light and moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong acids, strong bases, strong oxidizing agents and strong reducing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 144-48-9
Molecular Formula C2H4INO
Molecular Weight (g/mol) 184.964
MDL Number MFCD00008028
InChI Key PGLTVOMIXTUURA-UHFFFAOYSA-N
Synonym iodoacetamide, monoiodoacetamide, surauto, acetamide, 2-iodo, 2-iodo-acetamide, usaf d-1, alpha-iodoacetamide, ccris 7710, unii-zrh8m27s79, n-3-methoxy-4-butoxybenzyl thiobarbituric acid
PubChem CID 3727
IUPAC Name 2-iodoacetamide
SMILES C(C(=O)N)I

Specifications

Melting Point 92°C to 95°(dried)
Assay Percent Range 98%, stabilized with ca 5% water
Quantity 5 g
UN Number UN2811
Beilstein 1739080
Sensitivity Light sensitive
Solubility Information Soluble in water,dimethyl formamide and ethanol. Slightly soluble in methanol.
Formula Weight 184.96
Percent Purity 98%
Chemical Name or Material Iodoacetamide, stabilized with ≈5 to 8% water

RUO – Research Use Only

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