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Thermo Scientific Chemicals 4-Epichlortetracycline hydrochloride, can be used as secondary standard

Product Code. 10105160
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Quantity:
100 mg
500 mg
Packaging:
Glass bottle

4-Epichlortetracycline hydrochloride, CAS # 14297-93-9, is a broad-spectrum, bacteriostatic antibiotic of the tetracycline antibiotic family.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• 4-Epichlortetracycline is the hydrochloride salt of 4-Epichlortetracycline, a tetracycline ring structure with a chloride substitution

• 4-Epichlortetracycline hydrochloride (4-Epi-chlortetracycline) is an epimer of chlortetracycline

• 4-Epichlortetracycline suppresses neutrophil activity and dampens the immune response

• Acts as an aminoacyl-tRNA analog to disrupt polypeptide synthesis, reducing bacterial growth Applications

• Can be used for in vitro research on cancer and inflammatory mechanisms

• Intended for use as a selective agent and secondary standard

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 101342-45-4
Molecular Formula C22H23ClN2O8·ClH
Molecular Weight (g/mol) 515.34
MDL Number MFCD09842537
InChI Key QYAPHLRPFNSDNH-PNEIEYGESA-N
Synonym epichlortetracycline hydrochloride
PubChem CID 92043146
IUPAC Name (4R,4aS,5aS,6R,12aR)-7-chloro-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride
SMILES CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C(C=CC(=C41)Cl)O)O)O)O)C(=O)N)N(C)C)O.Cl

Specifications

CAS Min % 96.0
CAS Max % 100.0
Melting Point 250.0°C
Color Orange to Yellow
Infrared Spectrum Authentic
Assay Percent Range 80% min. (as is,calculated)
Packaging Glass bottle
Quantity 500 mg
Solubility Information Solubility in water: 67g/L. Other solubilities: 20g/L methanol
Formula Weight 515.34
Percent Purity ≥97.0% Total Base (on anhydrous substance), ≥80 wt% (as is, calculated) (HPLC)
Physical Form Powder
Chemical Name or Material 4-Epichlortetracycline hydrochloride, 97%
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Product Identifier
  • 4-Epichlortetracycline hydrochloride
Signal Word
  • Warning
Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Reproductive toxicity Category 2
Hazard Statement
  • H319-Causes serious eye irritation.
  • H361d-Suspected of damaging the unborn child.
Precautionary Statement
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.

RUO – Research Use Only

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