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  7. 4EGI-1, Tocris Bioscience™

4EGI-1, Tocris Bioscience™

Product Code. 30002065
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Quantity:
10 mg
50 mg
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Description

Inhibits eIF4E:eIF4G subunit interaction

Inhibitor of eIF4E:eIF4G interaction; prevents eIF4E binding to eIF4G. Binds eIF4E and inhibits cap-dependent translation but not initiation factor-independent translation. Exhibits activity against Jurkat and A549 cells.

Chemical Identifiers

CAS 315706-13-9
Molecular Formula C18H12Cl2N4O4S
Molecular Weight (g/mol) 451.28
MDL Number MFCD02330020
InChI Key KFRKRECSIYXARE-UHFFFAOYSA-N
Synonym 2e-2-2-4-3,4-dichlorophenyl-1,3-thiazol-2-yl hydrazin-1-ylidene-3-2-nitrophenyl propanoic acid, 2z-2-4-3,4-dichlorophenyl-1,3-thiazol-2-yl hydrazinylidene-3-2-nitrophenyl propanoic acid, 2-4-3,4-dichlorophenyl thiazol-2 3h-ylidene hydrazono-3-2-nitrophenyl propanoic acid
PubChem CID 6911989
IUPAC Name 2-{2-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazin-1-ylidene}-3-(2-nitrophenyl)propanoic acid
SMILES OC(=O)C(CC1=CC=CC=C1[N+]([O-])=O)=NNC1=NC(=CS1)C1=CC(Cl)=C(Cl)C=C1

Specifications

Quantity 50 mg
Formula Weight 451.28
Percent Purity >98%
Chemical Name or Material Protein-synthesizing GTPase Compounds
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