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  7. 18762764

5-Fluorouracil, Tocris Bioscience™

Product Code. 18762764
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Quantity:
50 mg
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Description

Thymidylate synthetase inhibitor

Anticancer agent. Metabolized to form fluorodeoxyuridine monophosphate (FdUMP), fluorodeoxyuridine triphosphate (FdUTP) and fluorouridine (FUTP). FdUMP inhibits thymidylate synthase, causing a reduction in dTMP synthesis. FUTP and FdUTP are misincorporated into RNA and DNA respectively.

Specifications

CAS 51-21-8
Molecular Formula C4H3FN2O2
MDL Number MFCD00006018
Quantity 50 mg
Synonym 5-fluorouracil, fluorouracil, 5-fu, fluoroplex, adrucil, efudex, carac, fluracil, fluoroblastin, kecimeton
InChI Key GHASVSINZRGABV-UHFFFAOYSA-N
SMILES FC1=CNC(=O)NC1=O
IUPAC Name 5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione
Molecular Weight (g/mol) 130.08
PubChem CID 3385
ChEBI CHEBI:46345
Formula Weight 130.08
Percent Purity >99%
Chemical Name or Material 5-Fluorouracil
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