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  6. 8-Bromo-cGMP, sodium salt, Tocris Bioscience™

8-Bromo-cGMP, sodium salt, Tocris Bioscience™

Product Code. 18095822
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Quantity:
10 mg
50 mg
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Description

cGMP analog; activates PKG

Membrane permeable cGMP analog that activates protein kinase G (PKG). 4.3-fold more potent than cGMP in activating PKG1α and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro.

Chemical Identifiers

CAS 51116-01-9
Molecular Formula C10H11BrN5O7P
Molecular Weight (g/mol) 424.10
MDL Number MFCD00070128
InChI Key YUFCOOWNNHGGOD-UMMCILCDSA-N
Synonym 8-bromoguanosine-3',5'-cyclic monophosphate sodium salt
PubChem CID 131879957
IUPAC Name 9-[(4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxo-hexahydro-2λ⁵-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino-8-bromo-6,9-dihydro-3H-purin-6-one
SMILES NC1=NC(=O)C2=C(N1)N([C@@H]1O[C@@H]3COP(O)(=O)O[C@H]3[C@H]1O)C(Br)=N2

Specifications

Quantity 50 mg
Formula Weight 446.09
Percent Purity >98%
Chemical Name or Material 8-Bromo-cGMP, sodium salt
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