missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Tocris Bioscience™ a-Synuclein Degrader 2b
α-synuclein Degrader (PROTAC™)
Brand: Tocris Bioscience™ 8040/5
330.02 EUR valid until 2024-12-16
Use promo code "21630" to get your promotional price.
This item is not returnable.
View return policy
Description
α-Synuclein Degrader 2b is a selective α-synuclein Degrader (PROTAC™) (DC50 = 7.5 μM; Dmax = 89%). Comprises the probe molecule sery308, joined by a linker to a pomalidomide E3 ligase ligand. Activates both proteasomal and lysosomal degradation pathways. Protects SH-SY5Y cells from α-synuclein-induced cytotoxicity. Cell permeable.PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.Specifications
| 2-[[3-[5-(1,3-Benzodioxol-5-yl)-1H-pyrazol-3-yl]phenyl]amino]-N-[2-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethyl]acetamide | |
| 5 mg | |
| C39H41N7O10 |
| 2781922-42-5 | |
| Active Degraders | |
| 0.98 |