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  6. A23187, 98%, free acid, Thermo Scientific Chemicals

A23187, 98%, free acid, Thermo Scientific Chemicals

Product Code. 10397811 Shop All Thermo Scientific Chemicals Products
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Quantity:
1 mg
5 mg
Packaging:
Glass Bottle
Glass Bottle in Plastic Container
Unit Size:
1mg
5mg
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Product Code. 10397811

Brand: Thermo Scientific Acros 328080010

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Description

A23187 (Calcimycin), CAS # 52665-69-7, is a calcium ionophore-based antibiotic.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description


• A23187 is a polyether substance that permeabilizes cell membranes to calcium and other divalent cations


Applications
• A23187 can be used for the study of mitochondrial physiology because it acts as an uncoupling agent
• A23187 can be used to study the roles of divalent cations in cell physiology
• When bound to fluorescent calcium ions, A23187 can be useful for imaging studies

TRUSTED_SUSTAINABILITY

Identifiants chimiques

CAS 52665-69-7
Molecular Formula C29H37N3O6
Molecular Weight (g/mol) 523.63
MDL Number MFCD00151202,MFCD00151202
InChI Key HIYAVKIYRIFSCZ-CVXKHCKVSA-N
PubChem CID 97043288
IUPAC Name 5-(methylamino)-2-[[(2R,3S,5S,6S,8S,9S)-3,5,9-trimethyl-2-[(2S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl]-1,7-dioxaspiro[5.5]undecan-8-yl]methyl]-1,3-benzoxazole-4-carboxylic acid
SMILES CNC1=CC=C2OC(C[C@@H]3OC4(CC[C@@H]3C)O[C@H](C(C)C(=O)C3=CC=CN3)[C@H](C)C[C@H]4C)=NC2=C1C(O)=O

Spécification

Physical Form Solid
CAS Min % 97.5
CAS Max % 100.0
Melting Point 182.0°C to 193.0°C
Infrared Spectrum Authentic
Packaging Glass Bottle in Plastic Container
Color White
Quantity 1 mg
Assay Percent Range 98%
Merck Index 15, 1642
Solubility Information Solubility in water: .. Other solubilities: soluble in dmso, ethylacetate, methanol, ethanol
Formula Weight 523.63
Percent Purity 98%
Chemical Name or Material A23187, Free acid
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Sécurité et traitement

compliance-icons
Identifiant produit
  • A23187 (free acid)
 Mention d'avertissement
  • Warning
 Catégorie de danger
  • Acute toxicity Category 4
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Mention de danger
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
  • H312-Harmful in contact with skin.
  • H332-Harmful if inhaled.
  • H302-Harmful if swallowed.
 Conseils de prudence
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
  • P302+P352-IF ON SKIN: Wash with plenty of water/.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
FDS

RUO – Research Use Only

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