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  6. (±)-ADX71743, >98%;, Tocris Bioscience™

(±)-ADX71743, >98%;, Tocris Bioscience™

Product Code. 30000878
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Quantity:
10 mg
50 mg
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Description

Negative allosteric modulator at mGlu7; brain penetrant

Negative allosteric modulator at mGlu7 (IC50 = 300 nM). Blocks high frequency-induced LTP at SC-CA1 synapses in hippocampal slices in vitro. Increases evoked excitatory postsynaptic currents (eEPSCs) in mice. Brain penetrant.

Specifications

Linear Formula C17H19NO2
Quantity 10 mg
Solubility Information Soluble to 100mM in DMSO and to 100mM in ethanol
Formula Weight 269.34
Percent Purity >98%
Chemical Name or Material 6-(2,4-Dimethylphenyl)-2-ethyl-6,7-dihydro-4(5H)-benzoxazolone
Grade >98%
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