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  7. Aflatoxin B1, crystalline, Thermo Scientific Chemicals

Aflatoxin B1, crystalline, Thermo Scientific Chemicals

Product Code. 10593011
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Quantity:
1 mg
10 mg
50 mg
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Regulatory: Restrictions may apply to the purchase of this product and we may need to request additional documentation from you
This item is not returnable. View return policy
Regulatory: Restrictions may apply to the purchase of this product and we may need to request additional documentation from you

Description

Aflatoxin B1, crystalline, CAS # 1162-65-8, is a member of a group of mycotoxins presenting potent hepatotoxic and carcinogenic activities.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information

• Aflatoxin B1 (AFB1) is a member of a group of mycotoxins produced by Aspergillus flavus, and Aspergillus parasiticus showing carcinogenic activities
• AFB1 can induce the transversion of G to T in the third position of codon 249 of the p53 tumor suppressor gene, resulting in a mutation and promoting the carcinogenic process

Applications

• Aflatoxin B1 shows teratogenic activity
• It is a CYP1A2, CYP2A6, CYP2D6, and CYP3A substrate and can be used to study the CYP family in in vitro and in vivo studies.
• It can cause immunosuppression in animal models.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1162-65-8
Molecular Formula C17H12O6
Molecular Weight (g/mol) 312.28
MDL Number MFCD00869647
InChI Key OQIQSTLJSLGHID-UHFFFAOYNA-N
Synonym ccris 12, aflatoxin b, 2,3,6aalpha,9aalpha-tetrahydro-4-methoxycyclopenta c furo 3',2':4,5 furo 2,3-h 1 benzopyran-1,11-dione, aflatoxin-b1, unii-9n2n2y55mh, afb1, 1h,11h-cyclopenta c furo 3',2':4,5 furo 2,3-h 1 benzopyran-1,11-dione,2,3,6a,9a-tetrahydro-4-methoxy-, 6ar,9as, cyclopenta c furo 3',2':4,5 furo 2,3-h 1 benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy-, 6ar,9as, aflatoxin b1, cyclopenta c furo 3',2':4,5 furo 2,3-h 1 benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy
PubChem CID 186907
ChEBI CHEBI:2504
IUPAC Name 11-methoxy-6,8,19-trioxapentacyclo[10.7.0.0²,⁹.0³,⁷.0¹³,¹⁷]nonadeca-1,4,9,11,13(17)-pentaene-16,18-dione
SMILES COC1=C2C3=C(C(=O)CC3)C(=O)OC2=C2C3C=COC3OC2=C1

Specifications

Packaging Glass bottle
Quantity 1 mg
Merck Index 15, 171
Formula Weight 312.27
Chemical Name or Material Aflatoxin B1

Safety and Handling

compliance-icons compliance-icons
Product Identifier
  • Aflatoxin B1
 Signal Word
  • Danger
 Hazard Category
  • Acute toxicity Category 1
  • Acute toxicity Category 2
  • Carcinogenicity Category 1A
 Hazard Statement
  • H300-Fatal if swallowed.
  • H310-Fatal in contact with skin.
  • H330-Fatal if inhaled.
  • H350-May cause cancer.
 Precautionary Statement
  • P201-Obtain special instructions before use.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.
  • P310-Immediately call a POISON CENTER/doctor/.
  • P361-Take off immediately all contaminated clothing.
 Supplemental information
  • MIXTURE LIST-Contains : Aflatoxine AFB1

RUO – Research Use Only

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