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Apoptosis Activator 2, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Apoptosis activator; promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. Increases procaspase-9 processing and subsequent caspase-3 activation. Induces apoptosis in tumor cells (IC50 = 4 - 9 μM for leukemia cells) with weak or no effect on normal cell lines or those defective/deficient in Apaf-1, caspase-9 or caspase-3 activity (IC50 > 40 μM).
Specifications
Specifications
Quantity | 50 mg |
Formula Weight | 306.14 |
Percent Purity | >99% |
Chemical Name or Material | Apoptosis Activator 2 |
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