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Cytiva BioTrak™ MMP-2 Activity Assay

Provides a simple, specific and precise quantitative determination of active or pro MMP-2 in tissue culture supernatants, serum, plasma, urine, synovial fluid and tissue homogenates

Brand:  Cytiva RPN2631


Product Code. 10301335

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Description

Description

  • Specific for Matrix Metalloproteinase-2 (MMP-2)
  • Either the endogenous (naturally occurring) or total (following activation using APMA) activity levels in samples can be detected
  • Range and sensitivity equivalent to ELISA
  • Non-radioactive coated microplate format for ease of use
  • Measures active MMPs from a range of species, including human, mouse, rat, rabbit and porcine
  • Applicable for complex biological samples such as serum, plasma, synovial fluids, tissue extracts, cell culture supernatants
  • Flexible protocol to cover speed and sensitivity requirements

TRUSTED_SUSTAINABILITY
Specifications

Specifications

MMP-2
Matrix Metalloproteinase-2, Biotrak Assay
100 μL
-15°C to -30°C
The assay recognises the pro and active forms of MMP-2. It does not cross-react with other MMPs or TIMPs. Cross-reactivity has also been shown with rabbit, porcine, rat and mouse samples. Both pro and active MMP-2/TIMP-2 complexes as well as active MMP-2/
0.75 ng/ml/ (0.19 ng/ml possible with longer incubation)-12 ng/ml (3 ng/ml possibile with longer incubation)
66000
0.5 ng/mL (short incubation), 190 pg/mL (longer incubation)
ELISA
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Safety and Handling

Safety and Handling

Signal Word
  • Danger

Hazard Category
  • LONG-TERM AQUATIC HAZARD Chronic 3
  • Skin corrosion/irritation Category 2
  • Serious eye damage/eye irritation Category 2
  • Acute toxicity Category 4
  • Acute toxicity Category 2
  • Acute toxicity Category 1
  • Specific target organ toxicity after repeated exposure Category 2
  • ACUTE AQUATIC Acute 1
  • LONG-TERM AQUATIC HAZARD Chronic 1

Hazard Statement
  • H412-Harmful to aquatic life with long lasting effects.
  • H319-Causes serious eye irritation.
  • H315-Causes skin irritation.
  • H302-Harmful if swallowed.
  • H332-Harmful if inhaled.
  • H300-Fatal if swallowed.
  • H310-Fatal in contact with skin.
  • H330-Fatal if inhaled.
  • H373-May cause damage to organs.
  • H400-Very toxic to aquatic life.
  • H410-Very toxic to aquatic life with long lasting effects.

Precautionary Statement
  • P273-Avoid release to the environment.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P264-Wash thoroughly after handling.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P271-Use only outdoors or in a well-ventilated area.
  • P270-Do not eat, drink or smoke when using this product.
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P262-Do not get in eyes, on skin, or on clothing.
  • P260-Do not breathe dust/fume/gas/mist/vapours/spray.
  • P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
  • P302-if on skin: .
  • P405-Store locked up.
  • P501-Dispose of contents/container to .

Supplemental information
  • MIXTURE LIST-Contains : 2-amino-2-(hydroxymethyl)propane-1, 3-diol hydrochloride, zinc chloride, trometamol, S-2444 substrat

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