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Brepocitinib P-Tosylate, MedChemExpress
MedChemExpress Brepocitinib (PF-06700841) P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. Brepocitinib P-Tosylate also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6.49 μM, respectively.
Brand: Medchem Express HY-112708A
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Description
Brepocitinib (PF-06700841) P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. Brepocitinib P-Tosylate also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6.49 μM, respectively.Specifications
Brepocitinib P-Tosylate | |
White | |
C25H29F2N7O4S | |
PF-06700841 P-Tosylate | |
O=C([C@H]1C(F)(F)C1)N2C3CN(C4=NC(NC5=CN(C)N=C5)=NC=C4)CC2CC3.O=S(C6=CC=C(C)C=C6)(O)=O | |
561.6 | |
Research | |
COVID-19-immunoregulation |
2140301-96-6 | |
Research | |
100 mg | |
DMSO : 62.5 mg/mL (111.29 mM; Need ultrasonic) | |
561.6 | |
99.69% | |
Solid |
Research purposes only