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  6. CC 401 dihydrochloride, Tocris Bioscience™

CC 401 dihydrochloride, Tocris Bioscience™

Product Code. 30001031
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

High affinity JNK inhibitor; also inhibits HCMV replication

High affinity JNK inhibitor (Ki values are 25-50 nM). Inhibits JNK via competitive binding of the ATP-binding site of active, phosphorylated JNK. Exhibits > 40-fold selectivity for JNK over p38, ERK, IKK2, protein kinase C, Lck and ZAP70. Hepatoprotective. Also inhibits HCMV replication.

Chemical Identifiers

CAS 2250025-96-6
Synonym CC 401 dihydrochloride

Specifications

Linear Formula C22H24N6O.2HCl
Quantity 10 mg
Solubility Information Soluble to 100mM in water and to 100mM in DMSO
Formula Weight 461.39
Percent Purity >98%
Physical Form Solid
Chemical Name or Material 3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole dihydrochloride
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