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Cilomilast, MedChemExpress

MedChemExpress Cilomilast (SB-207499) is a potent, selective and orally active inhibitor of Phosphodiesterase 4 (PDE4), with IC50s of ∼100 and 120 nM for LPDE4 and HPDE4, respectively.

Brand: Medchem Express HY-10790

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Product Code. 16464158

167.40 € / 10mg

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Description

Cilomilast shows selectivity for PDE4 over PDE1, PDE2, PDE3 and PDE5 (IC50=74, 65, >100, and 83 μM, respectively). Cilomilast has anti-inflammatory and immunomodulatory effects and can be used for thr research of asthma and chronic obstructive pulmonary disease (COPD).

Specifications

Chemical Name or Material	Cilomilast
Color	White
Molecular Formula	C₂₀H₂₅NO₄
Synonym	SB-207499
SMILES	O=C([C@H]1CC[C@@](C#N)(CC1)C2=CC=C(OC)C(OC3CCCC3)=C2)O
Formula Weight	343.42
Grade	Research
For Use With (Application)	COVID-19-immunoregulation

CAS	153259-65-5
Purity Grade Notes	Research
Quantity	10 mg
Solubility Information	DMSO : ≥ 100 mg/mL (291.19 mM)
Molecular Weight (g/mol)	343.42
Percent Purity	99.89%
Physical Form	Solid

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Cilomilast, MedChemExpress

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