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Invitrogen™ Desmoglein 1 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5121240
Description
Positive test controls include: A-431, HeLa, 293T, BT-474. The target is usually found in the following locations: Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome. Immunogen sequence: SPHFGTTTVI SESTYPSGPG VLHPKPILDP LGYGNVTVTE SYTTSDTLKP SVHVHDNRPA SNVVVTERVV GPISGADLHG MLEMPDLRDG SNVIVTERVI APSSSLPTSL TIHHPRESSN VVVTERVIQP TSGMIGSLSM HPELANAHNV IVTERVVSGA GVTGISGTTG ISGGIGSSGL VGTSMGAGSG ALSGAGISGG GIGLSSLGGT ASIGHMRSSS DHHFNQTIGS ASPSTARSRI TKYSTVQYSK.
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
Specifications
| Desmoglein 1 | |
| Polyclonal | |
| Unconjugated | |
| DSG1 | |
| Cadherin family member 4; CDHF4; desmoglein 1; desmoglein 1 beta; desmoglein 1 gamma; desmoglein-1; Desmosomal glycoprotein 1; DG1; DSG; DSG1; Dsg1b; Dsg1c; EPKHE; EPKHIA; Pemphigus foliaceus antigen; PPKS1; SPPK1 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 1828, 291755 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.67 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q02413 | |
| DSG1 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 800-1049 of human DSG1 (NP_001933.2). | |
| 100 μL | |
| Primary | |
| Human, Rat | |
| Antibody | |
| IgG |
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