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Thermo Scientific™ DMF-dG Phosphoramidite, standard grade, 28-400 finish bottle

DMF-dG CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxyguanosine (dG) with Dimethylaminoformamidine (DMF) base protection, for use in oligonucleotide synthesis.

Brand:  Thermo Scientific™ 27-1737-13

15.15 EUR valid until 2024-12-31
Use promo code "21651" to get your promotional price.


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Product Code. 17947172

  • 18.70 € / 2g

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Description

Description

DMF-dG CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxyguanosine (dG) with Dimethylaminoformamidine (DMF) base protection, for use in oligonucleotide synthesis. DNA phosphoramidites are the building blocks for synthesis of DNA or DNA containing oligonucleotides. Each base has unique protecting groups designed specifically to protect the DNA during the chemical synthesis process and produce the highest amount of full length product. Alternative protecting groups on dC (acetyl) and dG (DMF) allow for a faster deprotection of the oligonucleotide. By using Ac-dC, Bz-dA, and DMF-dG monomers, fast cleavage and deprotection can be effected by a 1:1 mixture of aqueous ammonium hydroxide and aqueous methylamine (or AMA) in 10 min. This product is supplied in a 30 mL Amber bottle with a 28-400 Finish neck style, which is compatible with most MerMade Systems of oligonucleotide synthesizers.

Features:
Full chemical name: 5'-O-(4,4'-Dimethoxytrityl)-N2-(dimethylaminoformamidine)-2'-deoxyguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
Molecular formula: C43H53N8O7P
Base: dG
Base Protection: DMF
Formula weight: 824.9 g/mol
CAS number: 330628-04-1
HPLC Purity: ≥98.0%; M-11 Impurity ≤0.01%
31P NMR Purity: ≥98.0%; Sum of non-primary peaks at 140-152 ppm (PIII impurities): ≤1.5%

TRUSTED_SUSTAINABILITY
Specifications

Specifications

MerMade Synthesizers
Store in freezer (at or below -20°C).
Fast deprotection
98%
Phosphoramidite
DNA
DMF-dG CEP
Deoxyguanosine (dG)
Room Temperature
2 g
Standard
Powder
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