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Donepezil hydrochloride, Tocris Bioscience™

Product Code. 18792704
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Potent AChE inhibitor

Potent acetylcholinesterase inhibitor (IC50 = 5.7 nM). Displays 1252-fold selectivity for AChE over BuChE (IC50 = 7138 nM for BuChE). Orally active.

Deuterated analog also available.

Chemical Identifiers

CAS 120011-70-3
Molecular Formula C24H30ClNO3
Molecular Weight (g/mol) 415.96
MDL Number MFCD00881312
InChI Key XWAIAVWHZJNZQQ-UHFFFAOYNA-N
Synonym donepezil hydrochloride, donepezil hcl, aricept, bnag, donepezilhcl, aricept odt, 2-1-benzylpiperidin-4-yl methyl-5,6-dimethoxy-2,3-dihydro-1h-inden-1-one hydrochloride, e 2020 pharmaceutical, eranz
PubChem CID 5741
ChEBI CHEBI:4696
IUPAC Name hydrogen 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one chloride
SMILES [H+].[Cl-].COC1=CC2=C(C=C1OC)C(=O)C(CC1CCN(CC3=CC=CC=C3)CC1)C2

Specifications

Quantity 50 mg
Formula Weight 415.95
Percent Purity >99%
Chemical Name or Material Donepezil hydrochloride
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