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Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format
Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.
Brand: Thermo Scientific™ 21655
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Description
Thermo Scientific™ Pierce DSS, also called disuccinimidyl suberate, is noncleavable and membrane permeable crosslinker that contains an amine-reactive N-hydroxysuccinimide (NHS) ester at each end of an 8-carbon spacer arm.
Highlights:
- Chemical crosslinking of intracellular proteins prior to cell lysis and immunoprecipitation
- “Fix” protein interactions to allow identification of weak or transient protein interactions
- Protein crosslinking to create bioconjugates via single-step reactions
- Crosslink oriented antibodies to Protein A or G agarose
- Immobilize proteins onto amine-coated surfaces
Specifications
| Amine-Amine | |
| DSS | |
| No | |
| Upon receipt store desiccated at 4°C. | |
| Ambient | |
| Chemical Labeling | |
| NHS Ester | |
| Powder | |
| DMF, DMSO | |
| No |
| No | |
| 368.35 | |
| 11.4 Å | |
| Yes | |
| Pierce™ | |
| Homobifunctional | |
| Medium (10 to 30 Å) | |
| 50 mg | |
| Standard, Single-use | |
| Crosslinker |
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Product Title
For Research Use Only. Not for use in diagnostic procedures.
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