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Tocris Bioscience™ Galiellalactone

STAT3 inhibitor; active in vivo

Brand:  Tocris Bioscience™ 6218/500U

245.35 EUR valid until 2024-12-16
Use promo code "21630" to get your promotional price.


Product Code. 18751368

  • 310.00 € / 500µg

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Description

Description

Galiellalactone is a STAT3 inhibitor. Irreversibly binds STAT3 and inhibits binding to DNA. Inhibits IL-6-dependent JAK/STAT signaling. Induces cell-cycle arrest in G2/M phase and apoptosis in androgen-insensitive prostate cancer cells via activation of ATM/ATR pathway. Also destabilizes microtubules and inhibits cell migration. Exhibits anticancer effects in a mouse tumor xenograft model.
Specifications

Specifications

Inhibitor
133613-71-5
194.23g/mol
STAT Inhibitors
STAT
C11H14O3
Store at -20°C
500 μg
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