missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Isoquinolines and derivatives
  7. GRI 977143, Tocris Bioscience™

GRI 977143, Tocris Bioscience™

Product Code. 30001547
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective LPA2 receptor non-lipid agonist

Selective lysophosphatidic acid 2 (LPA2) receptor non-lipid agonist (EC50 = 3.3 μM). Does not activate other LPA GPCRs at concentrations up to 10 μM. Antiapoptotic; inhibits activation of caspases 3, 7, 8 and 9, Bax translocation and PARP-1 cleavage. Activates ERK1/2 survival pathway.

Chemical Identifiers

CAS 325850-81-5
Molecular Formula C22H17NO4S
Molecular Weight (g/mol) 391.441
InChI Key GMVZUCHUOYUMLL-UHFFFAOYSA-N
Synonym unii-m3l07r4zep, m3l07r4zep, 2-3-1,3-dioxo-1h-benz de isoquinolin-2 3h-yl propyl thio benzoic acid, 2-3-1,3-dioxo-1h-benzo de isoquinolin-2 3h-yl propyl thio benzoic acid, 2-3-1,3-dioxo-1h benzo de isoquinolin-2 3h-yl propyl thio benzoic acid, 2-3-1,3-dioxo-1h-benzo de isoquinolin-2 3h-yl propyl sulfanyl benzoic acid, 2-3-2,4-dioxo-3-azatricyclo 7.3.1.0?, 1 3 trideca-1 13 ,5,7,9,11-pentaen-3-yl propyl sulfanyl benzoic acid, 2-3-1,3-dioxo-1h,3h-benzo de isoquinolin-2-yl-propylsulfanyl-benzoic acid
PubChem CID 3114900
IUPAC Name 2-[3-(1,3-dioxobenzo[de]isoquinolin-2-yl)propylsulfanyl]benzoic acid
SMILES C1=CC=C(C(=C1)C(=O)O)SCCCN2C(=O)C3=CC=CC4=C3C(=CC=C4)C2=O

Specifications

Quantity 50 mg
Formula Weight 391.44
Percent Purity >98%
Chemical Name or Material GRI 977143
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.