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Tocris Bioscience™ GSK 626616

Potent and selective DYRK inhibitor; orally bioavailable.

285.00 € - 1050.00 €

Specifications

Chemical Name or Material (5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-4(5H)-thiazolone
CAS 1025821-33-3
Molecular Formula C18H10Cl2N4OS
Formula Weight 401.27
Purity 98%
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Product Code Brand Quantity Price Quantity & Availability  
18708926
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Tocris Bioscience™
6638/10
10 mg
285.00 €
10mg
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18758486
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Tocris Bioscience™
6638/50
50 mg This item is currently unavailable or has been discontinued.
View the product page for possible alternatives.
N/A
Description

Description

  • Potent and selective DYRK inhibitor (IC50 = 0.7 nM for DYRK3, similar potency for DYRK1 and 2)
  • Exhibits ∼20-fold selectivity over casein kinase 2 and negligible activity against a panel of 451 kinases screened
  • Enhances number of CFU-E stimulated by Epo from human marrow
  • Increases hemoglobin levels in anemic mice
  • Orally bioavailable
Specifications

Specifications

(5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-4(5H)-thiazolone
C18H10Cl2N4OS
98%
1025821-33-3
401.27
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Safety and Handling

Safety and Handling

Recommended Storage : Store at 4°C

SDS
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Documents

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