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Novus Biologicals™ Imiquimod, TLR7 ligand
Applications: Functional, In vitro assay, Ligand Activation
Brand: Novus Biologicals™ NBP2-26228-0.125mg
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Description
Imiquimod, TLR7 ligand is an imidazoquinoline amine analog to guanosine. As a synthetic molecule of the Imidazoquinoline family, it has potent immunostimulatory activity. Imiquimod has been shown to activate only TLR7. This activation is MyD88 dependant and leads to the induction of the transcription factor NF-kB. Buffer: 125μg in 50μL of DMSO (formerly supplied in sterile water) Endotoxin Note: <0.001 EU/μg MW: 276.8Specifications
| 2.5 mg/mL | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. | |
| This product is useful for activation of TLR7 and stimulation of TLR7 has been achieved with 5 to 10μL. Use in ligand activation, functional, and in vitro reported in scientific literature (PMID 25957979) | |
| Human/Mouse |
| C14H16N4, HCl | |
| 0.125 mg | |
| Imiquimod, TLR7 ligand |