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LEI 101 hydrochloride, Tocris Bioscience™
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Quantity:
10 mg
Description
Potent and selective CB2 partial agonist (pEC50 = 8.0). Exhibits >100-fold selectivity for CB2 over CB1 and no significant interaction with hFAAH, MAGL, DAGL or NAPE-PLD. Displays antinociceptive activity in a rat neuropathic pain model and attenuates renal inflammation in a mouse kidney damage model. Orally bioavailable with low brain penetration.
Specifications
Specifications
CAS | 2250025-91-1 |
Linear Formula | C23H25FN4O4S.HCl |
Quantity | 10 mg |
Synonym | LEI 101 hydrochloride |
Solubility Information | Soluble to 100mM in DMSO |
Formula Weight | 508.99 |
Physical Form | Solid |
Chemical Name or Material | 3-Cyclopropyl-1-[[4-[6-[(1,1-dioxido-4-thiomorpholinyl)methyl]-5-fluoro-2-pyridinyl]phenyl]methyl]-2 |
Grade | >98% |
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