Invitrogen™ Luminex™ 200™ Instrument System

Description

The Luminex 200 Instrument System sets the standard for multiplexing, providing the ability to perform up to 100 different tests in a single reaction volume on a flow cytometry-based platform. The Luminex 200 system is compatible with ProcartaPlex multiplex immunoassays and QuantiGene Plex multiplex gene expression assays.

Features of the Luminex system include:

• Multiplexing: up to 80 analytes per sample using magnetic microspheres
• Dynamic range (typical): ≥3.5 logs
• Read time: 96-well plate in ≤45 min (up to 12,800 tests/hour)
• Daily start-up/shut-down: ≤30 min

Available options

• Software: extra seat licenses, Basic Security Module, 21 CFR part 11 Module, Automation Module, LIS/LIMS Module
• Service: service contracts, IQ/OQ

Luminex xMAP technology

The open architecture of Luminex xMAP technology uses imaging, microspheres, digital signal processing, and traditional chemistry—combining proven technologies in a unique way.

Advantages of Luminex xMAP technology include:

• Helps reduce costs and labor through multiplexing
• Smaller sample size requirements compared to single result assays
• Enables fast, reproducible results from favorable kinetics of liquid bead array approach
• Broad coverage of applications, including protein expression and gene expression profiling

How Luminex xMAP technology works

Sets of magnetic microspheres are color-coded with combinations of red and infrared fluorophores. Each bead set is coated with a reagent specific to a particular bioassay, allowing the capture and detection of several specific analytes from a single sample. Optics in the compact analyzer excite the internal dyes that identify each microsphere as well as any reporter dye captured, providing quantitation of individual analytes on each microsphere. The analyzer reads many beads from each set, enabling rapid and precise results for several targets within a single sample.