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Tocris Bioscience™ ML 162
Inhibits glutathione peroxidase (GPX4); induces ferroptosis
185.74 € - 728.92 €
Specifications
Chemical Name or Material | 2-[(Chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide |
---|---|
CAS | 1035072-16-2 |
Target | Glutathione Peroxidase 4/GPX4 |
Molecular Formula | C23H22Cl2N2O3S |
Purity | 0.98 |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
30000030
|
Tocris Bioscience™
7821/10 |
10 mg |
185.74 €
10mg |
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30000010
|
Tocris Bioscience™
7821/50 |
50 mg |
728.92 €
50mg |
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Description
ML 162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor. It induces ferroptosis in vivo. It is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50 = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively).Specifications
2-[(Chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide | |
Glutathione Peroxidase 4/GPX4 | |
0.98 |
1035072-16-2 | |
C23H22Cl2N2O3S |
Safety and Handling
Recommended Storage : Store at -20°C