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Gibco™ Mouse FGF-4 Recombinant Protein, PeproTech®
E. coli Recombinant Protein
82.00 € - 3069.40 €
Specifications
Accession Number | P11403 |
---|---|
For Use With (Application) | Functional Assay |
Gene ID (Entrez) | 14175 |
Molecular Weight (g/mol) | 19 |
Name | Mouse FGF-4 |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17834363
|
Gibco™
450-57-100UG |
100 μg |
610.00 €
100µg |
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17804573
|
Gibco™
450-57-1MG |
2 x 500 μg | N/A | ||||||
30087730
|
Gibco™
450-57-01M |
2 x 500 μg |
3035.00 €
Pack of 2 |
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17853933
|
Gibco™
450-57-250UG |
250 μg |
1064.00 €
250µg |
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17843853
|
Gibco™
450-57-25UG |
25 μg |
199.00 €
25µg |
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17804793
|
Gibco™
450-57-500UG |
500 μg |
1818.00 €
500µg |
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17873853
|
Gibco™
450-57-5UG |
5 μg |
82.00 €
5µg |
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Description
Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.Specifications
P11403 | |
14175 | |
Mouse FGF-4 | |
-20°C | |
<1 EU/μg | |
Fgf4 | |
Unconjugated | |
APNGTRHAEL GHGWDGLVAR SLARLPVAAQ PPQAAVRSGA GDYLLGLKRL RRLYCNVGIG FHLQVLPDGR IGGVHADTRD SLLELSPVQR GVVSIFGVAS RFFVAMSSRG KLFGVPFFTD ECKFKEILLP NNYNAYESYA YPGMFMALSK NGRTKKGNRV SPTMKVTHFL PRL | |
≥ 95% by SDS-PAGE gel and HPLC analyses. |
Functional Assay | |
19 | |
E. coli | |
RUO | |
FGF; FGF4; Fgf-4; Fgfk; Fibroblast growth factor; fibroblast growth factor 4; fibroblast growth factor 4 splice isoform; HBGF-4; heparin secretory transforming protein 1; heparin secretory-transforming protein 1; heparin-binding growth factor 1; heparin-binding growth factor 4; HST; Hst1; hst-1; HSTF1; HSTF-1; human stomach cancer, transforming factor from FGF-related oncogene; kaposi sarcoma oncogene; Kfgf; K-FGF; K-fibroblast growth factor; KS3; oncogene HST; transforming protein KS3 | |
Mouse | |
Recombinant | |
Lyophilized |
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