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Neomycin sulfate hydrate, Thermo Scientific Chemicals
Description
Neomycin sulfate is an aminoglycoside antibiotic and calcium channel protein inhibitor. Neomycin sulfate also binds to prokaryotic ribosomes inhibiting translation and is effective against gram-positive and gram-negative bacteria. Neomycin sulfate inhibits Phospholipase C via binding to inositol phospholipids. It also inhibits phosphatidylcholine-PLD activity and induces Ca2+ mobilization and PLA2 activation in human platelets. Neomycin sulfate inhibits DNase I induced DNA degradation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Neomycin sulfate is an aminoglycoside antibiotic and calcium channel protein inhibitor. Neomycin sulfate also binds to prokaryotic ribosomes inhibiting translation and is effective against gram-positive and gram-negative bacteria. Neomycin sulfate inhibits Phospholipase C via binding to inositol phospholipids. It also inhibits phosphatidylcholine-PLD activity and induces Ca2+ mobilization and PLA2 activation in human platelets. Neomycin sulfate inhibits DNase I induced DNA degradation.
Solubility
Soluble in water
Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Specifications
Specifications
| Type | Neomycin Sulfate |
| Physical Form | Powder |
| Merck Index | 14,6454 |
| Solubility Information | Soluble in water |
| IUPAC Name | (2S,3R,4S,5S,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6R)-4,6-diamino-2-[(2R,3S,4R,5S)-4-[(2S,3R,4S,5R,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol;sulfuric acid |
| Formula Weight | 908.87 (Anhydrous) |
| Color | White |
| Quantity | 100 g |
| Chemical Name or Material | Neomycin sulfate hydrate |
Safety and Handling
- Neomycin sulfate hydrate
- Danger
- Reproductive toxicity Category 2
- Respiratory sensitiser Category 1
- Skin sensitiser Category 1
- H317-May cause an allergic skin reaction.
- H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
- H361d-Suspected of damaging the unborn child.
- P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P342+P311-If experiencing respiratory symptoms: Call a POISON CENTER/doctor/ .
- MIXTURE LIST-Contains : Neomycin sulfate
RUO – Research Use Only