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Nigericin sodium salt, Tocris Bioscience™

Product Code. 18722774
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Quantity:
10 mg
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Description

Selective K+ ionophore

Potassium ionophore, exchanges K+ for H+ across biological membranes, in a similar manner to Valinomycin (Cat. No. 3373). Stimulates mitochondral ATPase activity and disrupts membrane potential. Also acts as an ionophore for Pb2+ with no activity with other divalent cations. Antibiotic derived from Streptomyces hygroscopius.

Specifications

CAS 28643-80-3
Molecular Formula C40H67NaO11
Quantity 10 mg
Synonym nigericin sodium salt
InChI Key MOYOTUKECQMGHE-GZQLGCKCSA-M
SMILES CC1CCC(OC1C(C)C(=O)[O-])CC2CC(C(C3(O2)C(CC(O3)(C)C4CCC(O4)(C)C5C(CC(O5)C6C(CC(C(O6)(CO)O)C)C)C)C)C)OC.[Na+]
IUPAC Name sodium;(2R)-2-[(2R,3S,6R)-6-[[(2R,4R,5R,6R,7R,9R)-2-[(2R,5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-7-methoxy-2,4,6-trimethyl-1,10-dioxaspiro[4.5]decan-9-yl]methyl]-3-met
Molecular Weight (g/mol) 746.955
PubChem CID 131668656
Formula Weight 746.94
Percent Purity >98%
Chemical Name or Material Nigericin sodium salt
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