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o-Phenylenediamine, 98%, Thermo Scientific Chemicals
Description
o-phenylenediamine is used to prepare tiabendazole, pyrazinamide, morinamide, clemizole and chlormidazole. It is involved in the synthesis of benzimidazole by reacting with carboxylic acids and their derivatives. It is also used to prepare quinoxalinedione and mercaptoimidazoles by condensation with dimethyl oxalate and xanthate esters respectively. It reacts with nitrous acid to get benzotriazole, which finds application as a corrosion inhibitor. It is actively involved in the preparation of pharmaceuticals by reacting substituted o-phenylenediamine with various diketones.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
o-phenylenediamine is used to prepare tiabendazole, pyrazinamide, morinamide, clemizole and chlormidazole. It is involved in the synthesis of benzimidazole by reacting with carboxylic acids and their derivatives. It is also used to prepare quinoxalinedione and mercaptoimidazoles by condensation with dimethyl oxalate and xanthate esters respectively. It reacts with nitrous acid to get benzotriazole, which finds application as a corrosion inhibitor. It is actively involved in the preparation of pharmaceuticals by reacting substituted o-phenylenediamine with various diketones.
Solubility
Soluble in alcohol, chloroform, ether, slightly soluble in water. Soluble in hot water.
Notes
Moisture and air sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
Specifications
Specifications
| Melting Point | 100°C to 103°C |
| Density | 1.27 |
| Boiling Point | 256°C to 258°C |
| Flash Point | 136°C (277°F) |
| Assay Percent Range | 98% |
| Quantity | 25 g |
| UN Number | UN1673 |
| Beilstein | 606074 |
| Sensitivity | Air Sensitive |
| Merck Index | 14,7284 |
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Safety and Handling
- o-Phenylenediamine
- Danger
- Acute toxicity Category 3
- Acute toxicity Category 4
- LONG-TERM AQUATIC HAZARD Chronic 1
- ACUTE AQUATIC Acute 1
- Carcinogenicity Category 2
- Serious eye damage/eye irritation Category 2
- Germ cell mutagenicity Category 2
- Skin sensitiser Category 1
- H301-Toxic if swallowed.
- H312-Harmful in contact with skin.
- H317-May cause an allergic skin reaction.
- H319-Causes serious eye irritation.
- H332-Harmful if inhaled.
- H341-Suspected of causing genetic defects.
- H351-Suspected of causing cancer.
- H400-Very toxic to aquatic life.
- H410-Very toxic to aquatic life with long lasting effects.
- P273-Avoid release to the environment.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- MIXTURE LIST-Contains : 1,2-Benzenediamine
RUO – Research Use Only