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  8. OTS964 hydrochloride, MedChemExpress

OTS964 hydrochloride, MedChemExpress

Product Code. 16485876
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Product Code. 16485876

Brand: Medchem Express HY12467

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Description

MedChemExpress OTS964 hydrochloride is an orally active, high affinity and selective TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor with an IC50 of 28 nM. OTS964 hydrochloride is also a potent inhibitor of the cyclin-dependent kinase CDK11, which binds to CDK11B with a Kd of 40 nM.

OTS964 hydrochloride is an orally active, high affinity and selective TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor with an IC50 of 28 nM. OTS964 hydrochloride is also a potent inhibitor of the cyclin-dependent kinase CDK11, which binds to CDK11B with a Kd of 40 nM.

Specifications

Chemical Name or Material OTS964 hydrochloride
CAS 1338545-07-5
Color White
Purity Grade Notes Research
Molecular Formula C23H25ClN2O2S
Quantity 100 mg
Solubility Information DMSO : ≥ 83.33 mg/mL (194.26 mM) ∣H2O : 1.43 mg/mL (3.33 mM; Need ultrasonic)
SMILES OC1=CC(C)=C2C(C3=C(SC=C3)C(N2)=O)=C1C4=CC=C([C@@H](C)CN(C)C)C=C4.Cl
Molecular Weight (g/mol) 428.97
Formula Weight 428.97
Percent Purity 95.59%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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