missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Unclassified Organic Compounds
  6. OTX 015, Tocris Bioscience™

OTX 015, Tocris Bioscience™

Product Code. 30000982
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

BET bromodomain inhibitor; orally bioavailable

BET bromodomain inhibitor (IC50 values are in the range 92 - 112 nM). Inhibits proliferation and induces apoptosis of leukemia cell lines in vitro. Decreases BRD2, BRD4 and c-MYC protein expression. Orally bioavailable.

Chemical Identifiers

CAS 202590-98-5
Molecular Formula C25H22ClN5O2S
Molecular Weight (g/mol) 491.99
InChI Key GNMUEVRJHCWKTO-FQEVSTJZSA-N
Synonym Birabresib, unii-x40lks49s3, s-2-4-4-chlorophenyl-2,3,9-trimethyl-6h-thieno 3,2-f 1,2,4-triazolo 4,3-a 1,4 diazepin-6-yl-n-4-hydroxyphenyl acetamide, s-2-4-4-chlorophenyl-2,3,9-trimethyl-6h-thieno 3,2-f 1,2,4 triazolo 4,3-a 1,4 diazepin-6-yl-n-4-hydroxyphenyl acetamide, 6s-4-4-chlorophenyl-n-4-hydroxyphenyl-2,3,9-trimethyl-6h-thieno 3,2-f 1,2,4 triazolo 4,3-a 1,4 diazepine-6-acetamide, s-4-4-chlorophenyl-n-4-hydroxyphenyl-2,3,9-trimethyl-6h-thieno 3,2-f 1,2,4 triazolo 4,3-a 1,4 diazepine-6-acetamide, birabresib usan, otx-015 anhydrous, luzindole, interneuron, otx015 birabresib
PubChem CID 9936746

Specifications

Linear Formula C25H22ClN5O2S
Quantity 10 mg
Solubility Information Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight 491.99
Percent Purity >98%
Physical Form Solid
Chemical Name or Material (6S)-4-(4-Chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.