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  6. OTX 015, Tocris Bioscience™

OTX 015, Tocris Bioscience™

Product Code. 30000982
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

BET bromodomain inhibitor; orally bioavailable

BET bromodomain inhibitor (IC50 values are in the range 92 - 112 nM). Inhibits proliferation and induces apoptosis of leukemia cell lines in vitro. Decreases BRD2, BRD4 and c-MYC protein expression. Orally bioavailable.

Chemical Identifiers

CAS 202590-98-5
Molecular Formula C25H22ClN5O2S
Molecular Weight (g/mol) 491.99
InChI Key GNMUEVRJHCWKTO-FQEVSTJZSA-N
Synonym Birabresib, unii-x40lks49s3, s-2-4-4-chlorophenyl-2,3,9-trimethyl-6h-thieno 3,2-f 1,2,4-triazolo 4,3-a 1,4 diazepin-6-yl-n-4-hydroxyphenyl acetamide, s-2-4-4-chlorophenyl-2,3,9-trimethyl-6h-thieno 3,2-f 1,2,4 triazolo 4,3-a 1,4 diazepin-6-yl-n-4-hydroxyphenyl acetamide, 6s-4-4-chlorophenyl-n-4-hydroxyphenyl-2,3,9-trimethyl-6h-thieno 3,2-f 1,2,4 triazolo 4,3-a 1,4 diazepine-6-acetamide, s-4-4-chlorophenyl-n-4-hydroxyphenyl-2,3,9-trimethyl-6h-thieno 3,2-f 1,2,4 triazolo 4,3-a 1,4 diazepine-6-acetamide, birabresib usan, otx-015 anhydrous, luzindole, interneuron, otx015 birabresib
PubChem CID 9936746

Specifications

Linear Formula C25H22ClN5O2S
Quantity 10 mg
Solubility Information Soluble to 100mM in DMSO and to 20mM in ethanol
Formula Weight 491.99
Percent Purity >98%
Physical Form Solid
Chemical Name or Material (6S)-4-(4-Chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1
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