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  6. Thermo Scientific™ Pierce™ SMCC

Thermo Scientific™ Pierce™ SMCC

No-Weigh™ Format

149.00 € - 157.00 €

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Specifications

Chemical Reactivity Amine-Sulfhydryl
Cleavable By Thiols
Description SMCC
Molecular Weight (g/mol) 334.32
PEGylated No
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Thermo Scientific™
22360 		50 mg
149.00 €
50mg
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Thermo Scientific™
A35394 		10 x 1 mg
157.00 €
Pack of 10
Estimated Shipment: 11-12-2024
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Description

Description

Thermo Scientific™ Pierce SMCC is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane-stabilized spacer arm (8.3 Ås).

Highlights:

  • Cyclohexane bridge adds stability to the maleimide-reactive group; N-(4-carboxycyclohexylmethyl) maleimide groups are stable for 64 hours in 0.1 M sodium phosphate buffer, pH 7.0 at 4°C
  • Ideal for coupling enzymes to antibodies
  • Reactive groups: NHS-ester and maleimide
  • Reactive toward: amino and sulfhydryl groups
Specifications

Specifications

Amine-Sulfhydryl
SMCC
No
Upon receipt store desiccated at 4°C.
Ambient
Heterobifunctional
Short (<10 Å)
DMF, DMSO
No
By Thiols
334.32
8.3 Å
Yes
Chemical Labeling
Maleimide, NHS Ester
Powder
Standard, Single-use
Crosslinker
Videos
Safety and Handling

Safety and Handling

Product Identifier
  • SMCC

Signal Word
  • Warning

Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3

Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.

Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P264-Wash hands thoroughly after handling.
  • P271-Use only outdoors or in a well-ventilated area.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
  • P362+P364-Take off contaminated clothing and wash it before reuse.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.

Supplemental information
  • MIXTURE LIST-Contains : Succinimidyl-trans-4-(N-maleimidylmethyl)cyclohexane-1-carboxylate

SDS
Documents

Documents

Product Certifications

For Research Use Only. Not for use in diagnostic procedures.