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PLX-4720, MedChemExpress

MedChemExpress PLX-4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-RafV600E than wild-type B-Raf.

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86.40 € - 183.60 €

Specifications

Chemical Name or Material PLX-4720
CAS 918505-84-7
Color White
Purity Grade Notes Research
Molecular Formula C17H14ClF2N3O3S
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Product Code Brand Quantity Price Quantity & Availability  
16448158
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Medchem Express
HY-51424
10 mg
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10mg
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Medchem Express
HY-51424
50 mg
183.60 €
50mg
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Description

Description

PLX-4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-RafV600E than wild-type B-Raf.
Specifications

Specifications

PLX-4720
White
C17H14ClF2N3O3S
O=S(NC1=CC=C(C(C(C2=CNC3=NC=C(C=C23)Cl)=O)=C1F)F)(CCC)=O
413.83
Research
Cancer-Kinase/protease
918505-84-7
Research
DMSO : 100 mg/mL (241.65 mM; Need ultrasonic)
413.83
98.35%
Solid
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Safety and Handling

Safety and Handling

missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month

SDS
Documents

Documents

Product Certifications

Research purposes only

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