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PLX-4720, MedChemExpress
MedChemExpress PLX-4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-RafV600E than wild-type B-Raf.

86.40 € - 183.60 €
Specifications
Chemical Name or Material | PLX-4720 |
---|---|
CAS | 918505-84-7 |
Color | White |
Purity Grade Notes | Research |
Molecular Formula | C17H14ClF2N3O3S |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16448158
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Medchem Express
HY-51424 |
10 mg |
86.40 €
10mg |
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16424067
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Medchem Express
HY-51424 |
50 mg |
183.60 €
50mg |
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Description
PLX-4720 is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM in a cell-free assay, equally potent to c-Raf-1(Y340D and Y341D mutations), and 10-fold selectivity for B-RafV600E than wild-type B-Raf.Specifications
PLX-4720 | |
White | |
C17H14ClF2N3O3S | |
O=S(NC1=CC=C(C(C(C2=CNC3=NC=C(C=C23)Cl)=O)=C1F)F)(CCC)=O | |
413.83 | |
Research | |
Cancer-Kinase/protease |
918505-84-7 | |
Research | |
DMSO : 100 mg/mL (241.65 mM; Need ultrasonic) | |
413.83 | |
98.35% | |
Solid |
Safety and Handling
missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Research purposes only
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