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Invitrogen™ Predictor™ hERG Fluorescence Polarization Assay Kit

Predictor™ hERG Fluorescence Polarization Assay Kit

Brand:  Invitrogen™ PV5365

Product Code. 10532304

  • 1292.00 € / Each
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For Research Use Only. All usage must comply with product instructions.

This item is not returnable. View return policy

Description

Description

The Predictor™ hERG Fluorescence Polarization Assay Kit provides a set of validated components to perform hERG channel biochemical binding studies in the absence of radioligand. The assay was designed to identify potential hERG channel blockers by producing data that accurately correlates with patch-clamp electrophysiology studies. The assay is based on the principle of fluorescence polarization where a red-shifted fluorescent tracer is displaced from the hERG channel by compounds that bind to the channel. Assay performance was validated with a panel of established hERG channel blockers. Results from the Predictor™ assay demonstrate a high correlation with those obtained from patch clamp techniques.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Red
Fluorescence
1 Kit

PV5365 Predictor™ hERG Fluorescence Polarization Assay Kit
(Other materials are required separately; please refer to the protocol)
Includes:
• Predictor™ hERG Membranes
• Predictor™ hERG Tracer Red
• Predictor™ hERG Buffers
• E-4031
• Predictor™ hERG Fluorescence Polarization Assay Protocol
• Certificate of Analysis
Store the Predictor™ hERG Membranes at -80°C. The Predictor™ Tracer Red, Predictor™buffers, and E-4301 should be stored at -20°C.
Ion Channels
End Point
Predictor™ System
Predictor™
Assay Kit
Predictor hERG Tracer Red
Microplate Reader
384-well Plate
Biochemical binding
hERG
Dry Ice
hERG
Ion Channels
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For Research Use Only. Not for use in diagnostic procedures.