missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organosulfur Compounds
  6. Organic disulfides
  7. PX 12, Tocris Bioscience™

PX 12, Tocris Bioscience™

Product Code. 18015872
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Thioredoxin-1 inhibitor

Thioredoxin-1 (Trx-1) inhibitor; irreversibly inactivates Trx-1 as a substrate for reduction by thioredoxin reductase (TR); competitively inhibits the reduction of Trx-1 by TR (Ki = 30.8 μM). Attenuates expression of HIF-1α, VEGF and iNOS (IC50 values are 7.2, 10.4 and 18.1 μM respectively). Exhibits antitumor activity; directly inhibits tubulin in vitro and decreases tumor microvessel density in vivo.

Chemical Identifiers

CAS 141400-58-0
Molecular Formula C7H12N2S2
Molecular Weight (g/mol) 188.31
MDL Number MFCD18086851
InChI Key BPBPYQWMFCTCNG-UHFFFAOYNA-N
Synonym 2-sec-butyldisulfanyl-1h-imidazole, 2-1-methylpropyl dithio-1h-imidazole, 2-butan-2-yldisulfanyl-1h-imidazole, 1h-imidazole,2-1-methylpropyl dithio, 1h-imidazole, 2-1-methylpropyl dithio, iv 2 compound, iv-2 compound, 1-methylpropyl-2-imidazolyl disulfide
PubChem CID 219104
IUPAC Name 2-(butan-2-yldisulfanyl)-1H-imidazole
SMILES CCC(C)SSC1=NC=CN1

Specifications

Quantity 10 mg
Formula Weight 188.31
Percent Purity >99%
Chemical Name or Material PX 12
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.