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Tocris Bioscience™ Pyr 10
Selective TRPC3 inhibitor
187.00 € - 682.00 €
Specifications
| Chemical Name or Material | N-[4-[3,5-bis(Trifluoromethyl)-1 H-pyrazol-1-yl]phenyl]-4-methylbenzenesulfonamide |
|---|---|
| CAS | 1315323-00-2 |
| Target | TRPC Channel Blockers |
| Molecular Formula | C18H13F6N3O2S |
| Purity | 0.98 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18758536
|
Tocris Bioscience™
6941/10 |
10 mg |
187.00 €
10mg |
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|
18768946
|
Tocris Bioscience™
6941/50 |
50 mg |
682.00 €
50mg |
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Description
Pyr 10 is a TRPC3 (transient receptor potential canonical 3) channel inhibitor (IC50 = 0.72 μM for TRPC3 mediated calcium entry in vitro), which displays approximately 18-fold selectivity for TRPC3-mediated receptor operated calcium entry (ROCE) over STIM1/Orai1-mediated store operated calcium entry (SOCE). Pyr 10 inhibits NFATc3 activation and inhibits proliferation of rat ventricular cardiac fibroblasts.Specifications
| N-[4-[3,5-bis(Trifluoromethyl)-1 H-pyrazol-1-yl]phenyl]-4-methylbenzenesulfonamide | |
| TRPC Channel Blockers | |
| 0.98 |
| 1315323-00-2 | |
| C18H13F6N3O2S |
Safety and Handling
Recommended Storage : Store at -20°C