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  8. RS 39604 hydrochloride, Tocris Bioscience™

RS 39604 hydrochloride, Tocris Bioscience™

Product Code. 30001157
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Quantity:
10 mg
50 mg
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Description

5-HT4 antagonist

A potent and selective 5-HT4 antagonist, with a pKi of 9.1 at 5-HT4 receptors in guinea pig striatal membranes and greater than 1000-fold selectivity over 5-HT1A, 2C, 3 and D1, D2, M1, M2, AT1, B1 and α1C receptors. The ketone group gives RS 39604 a relatively long half life; it is also orally active and so suitable for in vivo studies.

Chemical Identifiers

CAS 167710-87-4
Molecular Formula C26H37Cl2N3O6S
Molecular Weight (g/mol) 590.557
InChI Key QSMYZGMJSGUWPM-UHFFFAOYSA-N
Synonym rs 39604 hydrochloride, gnf-pf-5475, n-2-4-3-4-amino-5-chloro-2-3,5-dimethoxybenzyl oxy phenyl-3-oxopropyl piperidin-1-yl ethyl methanesulfonamide hydrochloride, rs-39604 hydrochloride, 1-4-amino-5-chloro-2-methoxyphenyl-3-1-2-methylsulphonylamino ethyl-4-piperidinyl-1-propanone hydrochloride, 1-4-amino-5-chloro-2-3,5-dimethoxybenzyloxy phenyl-3-1-2-methylsulfonyl amino ethyl-4-piperidinyl-1-propanone hydrochloride, 1-4-amino-5-chloro-2-3,5-dimethoxyphenyl methyloxy-3-1-2-methylsulphonylamino ethyl piperidin-4-yl propan-1-one hydrochloride
PubChem CID 19081934
ChEBI CHEBI:64081
IUPAC Name N-[2-[4-[3-[4-amino-5-chloro-2-[(3,5-dimethoxyphenyl)methoxy]phenyl]-3-oxopropyl]piperidin-1-yl]ethyl]methanesulfonamide;hydrochloride
SMILES COC1=CC(=CC(=C1)COC2=CC(=C(C=C2C(=O)CCC3CCN(CC3)CCNS(=O)(=O)C)Cl)N)OC.Cl

Specifications

Quantity 10 mg
Formula Weight 590.56
Percent Purity >98%
Chemical Name or Material RS 39604 hydrochloride
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