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  6. (S)-Duloxetine hydrochloride, Tocris Bioscience™

(S)-Duloxetine hydrochloride, Tocris Bioscience™

Product Code. 30001596
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Quantity:
10 mg
50 mg
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This item is not returnable. View return policy

Description

Potent 5-HT and NA reuptake inhibitor (SNRI); also blocks dopamine reuptake

High affinity, competitive 5-HT and noradrenaline (NA) re-uptake inhibitor (Ki values are 8.5 and 45 nM for 5-HT and NA reuptake respectively in cortical synaptosomes; IC50 values are 28 and 46 nM for 5-HT and NA reuptake respectively in rat hippocampal slices). Also blocks dopamine reuptake (Ki = 300 nM in striatal synaptosomes). Exhibits antidepressant and anxiolytic effects. Orally bioavailable.

Chemical Identifiers

CAS 136434-34-9
Molecular Formula C18H20ClNOS
Molecular Weight (g/mol) 333.87
MDL Number MFCD06407958,MFCD06801358
InChI Key BFFSMCNJSOPUAY-LMOVPXPDSA-N
Synonym (+)-(S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propanamine hydrochloride
PubChem CID 87834970
IUPAC Name hydrogen methyl[(3S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl]amine chloride
SMILES [H+].[Cl-].CNCC[C@H](OC1=C2C=CC=CC2=CC=C1)C1=CC=CS1

Specifications

Quantity 50 mg
Formula Weight 333.88
Percent Purity >99%
Chemical Name or Material (S)-Duloxetine hydrochloride
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