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SKF 83566 hydrobromide, Tocris Bioscience™

Product Code. 18004272
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Quantity:
10 mg
50 mg
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Description

Potent, selective D1-like antagonist

Potent and selective D1-like dopamine receptor antagonist (Ki∽ 0.56 nM for D1; KB = 2 μM for D2). Also antagonist at the vascular 5-HT2 receptor (Ki = 11 nM). Displays selective inhibition of adenylyl cyclase 2 (AC2); inactive against AC1 or AC5. Centrally active following systemic administration in vivo.

Chemical Identifiers

CAS 108179-91-5
Molecular Formula C17H19Br2NO
Molecular Weight (g/mol) 413.153
InChI Key SDQJYYGODYRPBR-UHFFFAOYSA-N
Synonym skf 83566 hydrobromide, 8-bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1h-benzo d azepin-7-ol hydrobromide, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepin-7-ol hydrobromide, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepin-7-olhydrobromide, 8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol hydrobromide, 8-bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepin-7-ol hydrobromide
PubChem CID 23581817
IUPAC Name 8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol;hydrobromide
SMILES CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)Br.Br

Specifications

Quantity 10 mg
Formula Weight 413.15
Percent Purity >98%
Chemical Name or Material SKF 83566 hydrobromide
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