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SPDP, MedChemExpress
MedChemExpress SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).
Brand: Medchem Express HY-100216
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Description
SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).Specifications
| SPDP | |
| White | |
| C12H12N2O4S2 | |
| SPDP Crosslinker | |
| O=C(ON1C(CCC1=O)=O)CCSSC2=NC=CC=C2 | |
| 312.36 | |
| Research |
| 68181-17-9 | |
| Research | |
| 500 mg | |
| DMSO : 155 mg/mL (496.22 mM; Need ultrasonic) | |
| 312.36 | |
| 97.0% | |
| Solid |
Research purposes only