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  6. TM 5441, Tocris Bioscience™

TM 5441, Tocris Bioscience™

Product Code. 30002156
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Plasminogen activator inhibitor-1 (PAI-1) inhibitor

Plasminogen activator inhibitor-1 (PAI-1) inhibitor (IC50 = 3.58 - 60.3 μM). Increases apoptosis in human cancer cell lines. Reduces senescence and increases lifespan in mouse models of ageing (kl/kl). Inhibits L-NAME (Cat.No. 0665) induced systolic blood pressure increases, telomere length reduction and cardiac hypertrophy in mice. Renoprotective. Orally bioavailable.

Chemical Identifiers

Synonym TM 5441

Specifications

Linear Formula C21H16ClN2NaO6
Quantity 10 mg
Solubility Information Soluble to 100mM in DMSO
Formula Weight 450.8
Percent Purity >98%
Physical Form Solid
Chemical Name or Material 5-Chloro-2-[[2-[2-[[3-(3-furanyl)phenyl]amino]-2-oxoethoxy]acetyl]amino]benzoic acid sodium salt
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