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Trimethylsilyl cyanide, 97%, Thermo Scientific Chemicals
Description
Trimethylsilyl Cyanide is used as a reagent in the preparation of optically active cyanohydrins. It is used in the derivatization of complex metabolite mixtures by GC-MS. It is employed in the preparation of Reissert compounds, which represent reactive polyamides. Further, it is used to convert pyridine-N-oxides into 2-cyanopyridine. It is also used as a cyanide source in an enantioselective organocatalytic Strecker-type reaction of aliphatic N,N-dialkylhydrazones. In addition to this, it is used as a reagent for the cyanosilylation of aldehydes.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Trimethylsilyl Cyanide is used as a reagent in the preparation of optically active cyanohydrins. It is used in the derivatization of complex metabolite mixtures by GC-MS. It is employed in the preparation of Reissert compounds, which represent reactive polyamides. Further, it is used to convert pyridine-N-oxides into 2-cyanopyridine. It is also used as a cyanide source in an enantioselective organocatalytic Strecker-type reaction of aliphatic N,N-dialkylhydrazones. In addition to this, it is used as a reagent for the cyanosilylation of aldehydes.
Solubility
Miscible with organic solvents.
Notes
Moisture sensitive. Store in a cool place.Incompatible with water, strong oxidizing agents, strong reducing agents, strong acids and strong bases.
Specifications
Specifications
| Boiling Point | 118°C to 119°C |
| Melting Point | 11°C to 12°C |
| Quantity | 25 g |
| UN Number | UN3383 |
| Beilstein | 1737612 |
| Flash Point | 1°C (33°F) |
| Solubility Information | Miscible with organic solvents. |
| Formula Weight | 99.21 |
| Percent Purity | 97% |
| Odor | Almond-like |
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Safety and Handling
- Trimethylsilyl cyanide
- Danger
- Acute toxicity Category 1
- LONG-TERM AQUATIC HAZARD Chronic 1
- Flammable liquid Category 2
- H225-Highly flammable liquid and vapour.
- H300-Fatal if swallowed.
- H310-Fatal in contact with skin.
- H330-Fatal if inhaled.
- H410-Very toxic to aquatic life with long lasting effects.
- EUH014-Reacts violently with water.
- EUH029-Contact with water liberates toxic gas.
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P264-Wash face, hands and anyexposed skin thoroughly after handling.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P310-Immediately call a POISON CENTER/doctor/.
- P362+P364-Take off contaminated clothing and wash it before reuse.
- P405-Store locked up.
- MIXTURE LIST-Contains : Trimethylsilyl cyanide
RUO – Research Use Only
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