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Tris(2-carboxyethyl)phosphine hydrochloride, 95%, 0.5M soln. in water, Thermo Scientific Chemicals Product Code.: 15429365
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Tris(2-carboxyethyl)phosphine hydrochloride, 95%, 0.5M soln. in water, Thermo Scientific Chemicals

Product Code. 15429365
5 mL
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Quantity:
5 mL
25 mL
100 mL
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Product Code. 15429365

Brand: Thermo Scientific Alfa Aesar H51864.AA

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Description

Tris(2-carboxyethyl)phosphine hydrochloride is widely used as a reducing agent to reduce disulfide bonds in proteins and trans-4,5-dihydroxy-1,2-dithiane. It is involved in the reduction of sulfoxides, sulfonyl chlorides, N-oxides and azides. It plays an important role in the tissue homogenization process for RNA isolation. It acts as a chelating agent and forms complexes with various heavy metal ions such as Zn(II), Cd(II), Pb(II), and Ni(II). Furthermore, it is useful in the labeling of cysteine residues with maleimides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Tris(2-carboxyethyl)phosphine hydrochloride is widely used as a reducing agent to reduce disulfide bonds in proteins and trans-4,5-dihydroxy-1,2-dithiane. It is involved in the reduction of sulfoxides, sulfonyl chlorides, N-oxides and azides. It plays an important role in the tissue homogenization process for RNA isolation. It acts as a chelating agent and forms complexes with various heavy metal ions such as Zn(II), Cd(II), Pb(II), and Ni(II). Furthermore, it is useful in the labeling of cysteine residues with maleimides.

Solubility
Miscible with water and methanol.

Notes
Air sensitive. Store in cool place. Incompatible with strong oxidizing agents
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 51805-45-9
Molecular Formula C9H12O6P
Molecular Weight (g/mol) 247.16
MDL Number MFCD00145469
InChI Key PZBFGYYEXUXCOF-UHFFFAOYSA-K
Synonym tris 2-carboxyethyl phosphine hydrochloride, tcep hcl, tcep hydrochloride, 3,3',3-phosphinetriyltripropanoic acid hydrochloride, tcep, unii-h49aam893k, tris carboxyethyl phosphine hydrochloride, tris-2-carboxyethyl phosphine hydrochloride, tris 2-carboxyethyl phosphine hcl, 3,3',3-phosphinetriyltripropanoicacidhydrochlorideShow MoreShow Less
PubChem CID 2734570
IUPAC Name 3-[bis(2-carboxyethyl)phosphanyl]propanoic acid;hydrochloride
SMILES [O-]C(=O)CCP(CCC([O-])=O)CCC([O-])=O

Specifications

Linear Formula (HO2CCH2CH2)3P·HCl
Quantity 5 mL
UN Number UN3265
Solubility Information Miscible with water and methanol.
Formula Weight 286.65
Percent Purity 95%
Concentration or Composition (by Analyte or Components) 0.5M soln. in water
Chemical Name or Material Tris(2-carboxyethyl)phosphine hydrochloride

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5 results found
Lot Number Certificate Type Date Catalog Number
Lot NumberP10L055 Certificate TypeCertificate of Analysis Date12/03/2025 Catalog NumberH51864.AC,H51864.AA,H51864.AE
Lot NumberX14K044 Certificate TypeCertificate of Analysis Date05/11/2024 Catalog NumberH51864.AC,H51864.AA,H51864.AE
Lot Number10252789 Certificate TypeCertificate of Analysis Date16/10/2024 Catalog NumberH51864.AC,H51864.AA,H51864.AE
Lot NumberS21K024 Certificate TypeCertificate of Analysis Date27/06/2024 Catalog NumberH51864.AC,H51864.AA,H51864.AE
Lot NumberP01K056 Certificate TypeCertificate of Analysis Date08/03/2024 Catalog NumberH51864.AC,H51864.AA,H51864.AE

Safety and Handling

compliance-icons
Product Identifier
  • Tris(2-carboxyethyl)phosphine hydrochloride 0.5M aqueous solution
 Signal Word
  • Danger
 Hazard Category
  • Serious eye damage/eye irritation Category 1
  • Skin corrosion/irritation Category 1 B
 Hazard Statement
  • H314-Causes severe skin burns and eye damage.
  • H318-Causes serious eye damage.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.
 Supplemental information
  • MIXTURE LIST-Contains : Tris(2-carboxyethyl)phosphonium chloride
SDS

RUO – Research Use Only

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