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UCB 35625, Tocris Bioscience™

Product Code. 30001389
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Quantity:
1 mg
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent CCR1 and CCR3 antagonist

Potent chemokine CCR1 and CCR3 receptor antagonist. Inhibits MIP-1α-induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants (IC50 values are 9.57 and 93.8 nM respectively). Antagonizes CCR3-mediated entry of HIV-1 isolate 89.6 into NP-2 cells (IC50 = 57 nM).

Isomer also available.

Chemical Identifiers

CAS 202796-42-7
Molecular Formula C30H37Cl2IN2O2
Molecular Weight (g/mol) 655.44
InChI Key FOAFBMYSXIGAOX-UHFFFAOYSA-N
Synonym unii-hd099hot7h, unii-h942hgf14d, hd099hot7h, chembl34626, piperidinium, 1-1-cycloocten-1-ylmethyl-4-2,7-dichloro-9h-xanthen-9-yl carbonyl amino-1-ethyl-, iodide 1:1 , cis, piperidinium, 1-1-cycloocten-1-ylmethyl-4-2,7-dichloro-9h-xanthen-9-yl carbonyl amino-1-ethyl-, iodide 1:1 , trans, piperidinium, 1-1-cycloocten-1-ylmethyl-4-2,7-dichloro-9h-xanthen-9-yl carbonyl amino-1-ethyl-, iodide, cis, piperidinium, 1-1-cycloocten-1-ylmethyl-4-2,7-dichloro-9h-xanthen-9-yl carbonyl amino-1-ethyl-, iodide, trans, unii-e32u2esr7j component foafbmysxigaox-kekkvsgzsa-n, unii-e32u2esr7j component foafbmysxigaox-mumzcososa-n
PubChem CID 6918496
IUPAC Name 1-[(cyclooct-1-en-1-yl)methyl]-4-(2,7-dichloro-9H-xanthene-9-amido)-1-ethylpiperidin-1-ium iodide
SMILES [I-].CC[N+]1(CC2=CCCCCCC2)CCC(CC1)NC(=O)C1C2=C(OC3=C1C=C(Cl)C=C3)C=CC(Cl)=C2

Specifications

Quantity 1 mg
Formula Weight 655.44
Percent Purity >98%
Chemical Name or Material UCB 35625
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