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Tocris Bioscience™ UNC 1999
Potent and selective EZH2/EZH1 inhibitor
1110.00 €
Specifications
Purity | >99% |
---|---|
Product Type | UNC 1999 |
Molecular Weight (g/mol) | 569.74 |
Inhibitors | UNC 1999 |
Description
Potent and SAM-competitive EZH2/EZH1 lysine methyltransferase inhibitor (IC50 values are 10 and 45 nM, respectively). Selective for EZH2/EZH1 over a panel of other methyltransferases and non-epigenetic targets. Reduces H3K27me3 levels in vitro. Prolongs survival of MLL-AF9 bearing mice. Orally bioavailable.Negative Control also available.
Specifications
>99% | |
UNC 1999 | |
569.74 | |
UNC 1999 |
For Research Use Only