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Tocris Bioscience™ VTP 27999 trifluoroacetate

Highly potent and selective renin inhibitor

Brand:  Tocris Bioscience™ 5563/10

Encompass

Product Code. 15756926

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Description

Description

VTP 27999 trifluoroacetate is a highly potent and selective renin inhibitor (IC50 = 0.47 nM). Displays >1000-fold selectivity over related and unrelated off-targets. Blocks renin-stimulated ERK1/2 phosphorylation in vascular smooth muscle cells. Exhibits a different mode of action to aliskiren (Cat. No. 5491).
Specifications

Specifications

Methyl N-[2-[(R)-(3-Chlorophenyl)[(3R)-1-[[[(2S)-2-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propyl]amino]carbonyl]-3-piperidinyl]methoxy]ethyl]carbamate trifluoroacetate
1013937-63-7
10 mg
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