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Tocris Bioscience™ VTP 27999 trifluoroacetate
Highly potent and selective renin inhibitor
Brand: Tocris Bioscience™ 5563/10
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Description
VTP 27999 trifluoroacetate is a highly potent and selective renin inhibitor (IC50 = 0.47 nM). Displays >1000-fold selectivity over related and unrelated off-targets. Blocks renin-stimulated ERK1/2 phosphorylation in vascular smooth muscle cells. Exhibits a different mode of action to aliskiren (Cat. No. 5491).Specifications
| Methyl N-[2-[(R)-(3-Chlorophenyl)[(3R)-1-[[[(2S)-2-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propyl]amino]carbonyl]-3-piperidinyl]methoxy]ethyl]carbamate trifluoroacetate | |
| 10 mg | |
| C26H41ClN4O5.CF3CO2H | |
| >97% |
| 1013937-63-7 | |
| Additional Synthetic Protease Inhibitors | |
| 639.1 |